Notice of Subsidiary Closure

Amano Enzyme Mexico, S.A. de. C.V., has discontinued production in October 2020 and began the liquidation process on January 1, 2021.

Company Name: Amano Enzyme Mexico, S.A. de. C.V.

Location: Irapuato, GTO, Mexico

Business: Manufacturing of animal derived active pharmaceutical ingredients and food ingredients

For further information, please contact:

Amano Enzyme, Inc.

Management Strategy Office

Fumikazu Ishikawa

Email Address: aea.sales@amano-enzyme.com